Superficial variant of granular corneal dystrophy-description of four cases

Abstract

In this case series, we describe four members of a family with the phenotype of superficial variant of granular corneal dystrophy (GCD). The complete description of cases, clinical photographs, anterior segment optical coherence tomography and discussion of treatment outcome have been highlighted. The common symptom for which the patients sought medical attention was blurring of vision. Typical corneal lesions were fluffy, white, too numerous to count, and in the most superficial part of corneal stroma. In all cases, the lesions recurred in spite of the different modes of the initial treatment. The recurrent lesions were also abundant but superficial in location and were managed successfully. Based on anterior segment optical coherence tomography and clinical findings, we thus describe a superficial variant of GCD occuring in three generations of a family with onset before 6 years of age and which recurred even after the best of clearance.

Keywords

• alcohol epitheliectomy
• granular corneal dystrophy
• phototherapeutic keratectomy
• superficial variant