The title compound, C6H2F4N2O, displays amide bond lengths of 1.218 (3) Å and 1.366 (3) Å for the C=O and C—N bonds, respectively. The Cp—N—C—O (p = pyridine) torsion angle of 179.0 (2)° indicates an anti-conformation for the grouping. Intermolecular hydrogen bonding is observed between the amine N—H group and the carbonyl O atom, which generates chains of molecules propagating along the b-axis direction.