Breast Unit, Champalimaud Clinical Centre/Champalimaud Foundation,Avenida Brasilia, 1400-038, Lisboa, Portugal; Faculty of Medicine, Lisbon University,Avenida Professor Egas Moniz, 1649-028, Lisboa, Portugal; Corresponding author. Breast Unit, Champalimaud Clinical Centre/Champalimaud Foundation, Avenida Brasília, 1400-038, Lisboa, Portugal.
Joana Costa
Breast Unit, Champalimaud Clinical Centre/Champalimaud Foundation,Avenida Brasilia, 1400-038, Lisboa, Portugal
Pedro Morgado
AI4medimaging,Rua do Parque Poente, Lote 35, 4705-002, Braga, Portugal
Ronald Kates
Breast Unit, Champalimaud Clinical Centre/Champalimaud Foundation,Avenida Brasilia, 1400-038, Lisboa, Portugal
David Pinto
Breast Unit, Champalimaud Clinical Centre/Champalimaud Foundation,Avenida Brasilia, 1400-038, Lisboa, Portugal
Carlos Mavioso
Breast Unit, Champalimaud Clinical Centre/Champalimaud Foundation,Avenida Brasilia, 1400-038, Lisboa, Portugal
João Anacleto
Breast Unit, Champalimaud Clinical Centre/Champalimaud Foundation,Avenida Brasilia, 1400-038, Lisboa, Portugal
Marta Martinho
Breast Unit, Champalimaud Clinical Centre/Champalimaud Foundation,Avenida Brasilia, 1400-038, Lisboa, Portugal
Daniel Simões Lopes
INESC ID, Instituto Superior Técnico, Lisbon University,Rua Alves Redol 9, 1000-029, Lisboa, Portugal
Arlindo R. Ferreira
Breast Unit, Champalimaud Clinical Centre/Champalimaud Foundation,Avenida Brasilia, 1400-038, Lisboa, Portugal; Faculty of Medicine, Lisbon University,Avenida Professor Egas Moniz, 1649-028, Lisboa, Portugal
Vasileios Vavourakis
Department of Mechanical & Manufacturing Engineering, University of Cyprus,Dept. of Mechanical & Manufacturing Engineering University of Cyprus, Cyprus; Department of Medical Physics & Biomedical Engineering, University College London,Malet Place Engineering Building, University College London, Gower Street, London, WC1E 6BT, United Kingdom
Myrianthi Hadjicharalambous
Department of Mechanical & Manufacturing Engineering, University of Cyprus,Dept. of Mechanical & Manufacturing Engineering University of Cyprus, Cyprus
Marco A. Silva
Microsoft Corporation (Portugal),Rua do Fogo de Santelmo, Lote 2.07.02, Lisboa, Portugal
Nickolas Papanikolaou
Breast Unit, Champalimaud Clinical Centre/Champalimaud Foundation,Avenida Brasilia, 1400-038, Lisboa, Portugal
Celeste Alves
Breast Unit, Champalimaud Clinical Centre/Champalimaud Foundation,Avenida Brasilia, 1400-038, Lisboa, Portugal
Fatima Cardoso
Breast Unit, Champalimaud Clinical Centre/Champalimaud Foundation,Avenida Brasilia, 1400-038, Lisboa, Portugal
Maria João Cardoso
Breast Unit, Champalimaud Clinical Centre/Champalimaud Foundation,Avenida Brasilia, 1400-038, Lisboa, Portugal; NOVA Medical School, Campo dos Mártires da Pátria 130, 1169-056, Lisboa, Portugal
Introduction: Innovations in 3D spatial technology and augmented reality imaging driven by digital high-tech industrial science have accelerated experimental advances in breast cancer imaging and the development of medical procedures aimed to reduce invasiveness. Presentation of case: A 57-year-old post-menopausal woman presented with screen-detected left-sided breast cancer. After undergoing all staging and pre-operative studies the patient was proposed for conservative breast surgery with tumor localization. During surgery, an experimental digital and non-invasive intra-operative localization method with augmented reality was compared with the standard pre-operative localization with carbon tattooing (institutional protocol). The breast surgeon wearing an augmented reality headset (Hololens) was able to visualize the tumor location projection inside the patient’s left breast in the usual supine position. Discussion: This work describes, to our knowledge, the first experimental test with a digital non-invasive method for intra-operative breast cancer localization using augmented reality to guide breast conservative surgery. In this case, a successful overlap of the previous standard pre-operative marks with carbon tattooing and tumor visualization inside the patient’s breast with augmented reality was obtained. Conclusion: Breast cancer conservative guided surgery with augmented reality can pave the way for a digital non-invasive method for intra-operative tumor localization.