STAR Protocols (Dec 2022)
Protocol to examine the neural basis of symbolic and non-symbolic quantity processing in human brain with fMRI
Abstract
Summary: Number perception is among the basic cognitive abilities necessary to understand our environment. Here, we present a protocol to examine the neural underpinnings of numerosity comparison regarding symbolic and non-symbolic stimuli using functional magnetic resonance imaging (fMRI). This protocol gives instructions for screening participants, followed by steps to perform an event-related fMRI experiment and data analysis with SPM12. This protocol will be informative for investigating numerical cognition in various groups including children with dyscalculia or people at different developmental stages.For complete details on the use and execution of this protocol, please refer to Üstün et al. (2021) and Vatansever et al. (2020). : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.