New research progress on the role and mechanism of inflammation in aging and aging-related diseases
Bai Ke,
Zhang Shaotong,
Zhan Qiang,
Chen Zhiyang,
Ju Zhenyu
Affiliations
Bai Ke
Key Laboratory of Regenerative Medicine of Ministry of Education, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Institute of Aging and Regenerative Medicine，Jinan University，Guangzhou 510632, Guangdong, China
Zhang Shaotong
Key Laboratory of Regenerative Medicine of Ministry of Education, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Institute of Aging and Regenerative Medicine，Jinan University，Guangzhou 510632, Guangdong, China
Zhan Qiang
Key Laboratory of Regenerative Medicine of Ministry of Education, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Institute of Aging and Regenerative Medicine，Jinan University，Guangzhou 510632, Guangdong, China
Chen Zhiyang
Key Laboratory of Regenerative Medicine of Ministry of Education, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Institute of Aging and Regenerative Medicine，Jinan University，Guangzhou 510632, Guangdong, China
Ju Zhenyu
Key Laboratory of Regenerative Medicine of Ministry of Education, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Institute of Aging and Regenerative Medicine，Jinan University，Guangzhou 510632, Guangdong, China
The problem of aging population in China is becoming increasingly severe. Intervening aging and its related diseases, developing safe and effective strategies to delay aging process have become urgent scientific issues. Accumulation of chronic inflammation, a common feature of multi-tissues in the elder, promotes cell and organism aging. This article reviews the role and underlying mechanisms of inflammation in aging and age-related diseases, as well as the anti-aging interventions targeting on inflammatory signals.
