Multifocal Tumefactive Demyelination Mimicking Intracranial Neoplasm

Abstract

Demyelinating disease presenting with clinical and radiologic features similar to a brain tumour is referred to as tumefactive demyelination. These lesions pose considerable diagnostic uncertainty. This is partly due to the atypical neurologic symptoms that the patient can present with as a consequence of the size, location, and potential for associated mass effect and oedema. The MRI appearance of these lesions can aid in preoperative diagnosis and assist with the final pathologic interpretation. We report a case of tumefactive demyelination where MRI played a vital role in arriving at a diagnosis. The diagnosis was confirmed histopathologically.

Keywords

• differential diagnosis
• mri
• ring enhancing