Journal of the Formosan Medical Association (Jan 2006)

Coexistence of Pernicious Anemia and Myasthenia Gravis—A Rare Combination of Autoimmune Diseases in Taiwan

  • Kuo-Hsuan Chang,
  • Rong-Kuo Lyu,
  • Long-Sun Ro,
  • Yih-Ru Wu,
  • Chiung-Mei Chen

DOI
https://doi.org/10.1016/S0929-6646(09)60181-9
Journal volume & issue
Vol. 105, no. 11
pp. 946 – 949

Abstract

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About 5-10% of patients with myasthenia gravis concomitantly have other autoimmune diseases. However, the coexistence of myasthenia gravis and pernicious anemia is rare. Here, we report a 73-year-old Taiwanese woman who developed myasthenia gravis 5 months after the onset of pernicious anemia. Her myasthenic and pernicious anemia symptoms markedly improved after pyridostigmine, prednisolone and hydroxo-cobalamine treatment. It is important to recognize concurrence of myasthenia gravis and pernicious anemia in the same patient because the therapeutic results for both diseases are rewarding.

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