PLoS ONE (Jan 2014)

HemI: a toolkit for illustrating heatmaps.

  • Wankun Deng,
  • Yongbo Wang,
  • Zexian Liu,
  • Han Cheng,
  • Yu Xue

DOI
https://doi.org/10.1371/journal.pone.0111988
Journal volume & issue
Vol. 9, no. 11
p. e111988

Abstract

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Recent high-throughput techniques have generated a flood of biological data in all aspects. The transformation and visualization of multi-dimensional and numerical gene or protein expression data in a single heatmap can provide a concise but comprehensive presentation of molecular dynamics under different conditions. In this work, we developed an easy-to-use tool named HemI (Heat map Illustrator), which can visualize either gene or protein expression data in heatmaps. Additionally, the heatmaps can be recolored, rescaled or rotated in a customized manner. In addition, HemI provides multiple clustering strategies for analyzing the data. Publication-quality figures can be exported directly. We propose that HemI can be a useful toolkit for conveniently visualizing and manipulating heatmaps. The stand-alone packages of HemI were implemented in Java and can be accessed at http://hemi.biocuckoo.org/down.php.