Histological tumor response predicts clinical outcome in patients with colorectal peritoneal metastasis treated with preoperative chemotherapy followed by cytoreduction and HIPEC

Abstract

Up to one quarter of the patients with colorectal cancer (CRC) develop peritoneal carcinomatosis (PM). The aims of this retrospective study were to characterize the histological response of the PM of CRC to preoperative chemotherapy and evaluate the potential prognostic value, in terms of survival.

Keywords

• colorectal cancer
• cytoreduction surgery
• histological response
• hyperthermic intraperitoneal chemotherapy
• peritoneal carcinomatosis
• peritoneal regression grading score
• preoperative chemotherapy
• tumor grading
• tumor regression