Nature Communications (Jul 2020)

A neurovascular high-frequency optical coherence tomography system enables in situ cerebrovascular volumetric microscopy

  • Giovanni J. Ughi,
  • Miklos G. Marosfoi,
  • Robert M. King,
  • Jildaz Caroff,
  • Lindsy M. Peterson,
  • Benjamin H. Duncan,
  • Erin T. Langan,
  • Amanda Collins,
  • Anita Leporati,
  • Serge Rousselle,
  • Demetrius K. Lopes,
  • Matthew J. Gounis,
  • Ajit S. Puri

DOI
https://doi.org/10.1038/s41467-020-17702-7
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 10

Abstract

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High resolution intravascular imaging in the brain is limited by the high tortuosity of the vasculature. Here the authors present a fiber optic imaging technology using high-frequency optical coherence tomography (HF-OCT) to provide volumetric high resolution images in the highly tortuous cerebral vasculature.