Antimicrobial resistance in pediatric patients with urinary tract infection

Abstract

Background: antimicrobial resistance in pediatric patients with urinary tract infection is a growing problem, with an important medical impact. Nowadays, resistance of E. coli, the main pathogen of this infection, to most of the antibiotics is a world health problem.Objective: to describe the microbiological pattern of antimicrobial resistance of the germs most frequently isolated in positive urine cultures at the laboratory of the “Mártires de Las Tunas” Pediatric Hospital, Las Tunas, during the year 2016.Methods: an observational, descriptive and cross-sectional study was conducted on all the urine cultures performed on patients with the order of bacteriological study, in the aforementioned institution and during the period herein declared. The following variables were assessed: culture positivity, isolated germs, antimicrobial resistance of microorganisms isolated in general and of E. coli in particular. The data were analyzed by using descriptive statistics.Results: 2811 urine cultures were analyzed, out of which 771 were positive, for 27,42 %; the predominating germ was E. coli in 77,69 % of the cases, followed by Klebsiella ssp in 11,54 %. The total of the isolated germs showed resistance to: ceftazidime (92,34 %), cefazolin (79,24 %), amoxicillin (66,66 %) and ampicillin (63,29 %). For the case of E. coli, the same resistance pattern remained with discretely higher values. The lower resistance of these microorganisms was to nitrofurantoin, about 3 %.Conclusions: the microbiological pattern of antimicrobial resistance of the most frequently isolated germs in positive urine cultures was described in the study.

Keywords

• urinary tract
• anti-infective agents
• urologic diseases
• escherichia coli