Toxicon: X (Oct 2019)

Intoxication with Ornithogalum arabicum is a potential cause of visual impairment and irreversible blindness in dogs

  • Inge J.M. Slenter,
  • Sylvia C. Djajadiningrat-Laanen,
  • Irma de Vries,
  • Marieke A. Dijkman

Journal volume & issue
Vol. 4

Abstract

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We describe two dogs with persistent visual impairment after initially mild intoxication signs following ingestion of Ornithogalum arabicum plant material. Additionally, a 12-year analysis of the Dutch Poisons Information Centre database additionally reveals that ingestion of Ornithogalum plant material can be potentially life-threatening to companion animals. Further studies are necessary to confirm the involvement of cardiac glycoside-like toxins present in Ornithogalum arabicum and the toxicity of these substances to the retina. Keywords: Ornithogalum arabicum, Cardiac glycosides, Retinal degeneration, Blindness