Nature Communications (Jan 2022)

Relative infectiousness of SARS-CoV-2 vaccine breakthrough infections, reinfections, and primary infections

  • Laith J. Abu-Raddad,
  • Hiam Chemaitelly,
  • Houssein H. Ayoub,
  • Patrick Tang,
  • Peter Coyle,
  • Mohammad R. Hasan,
  • Hadi M. Yassine,
  • Fatiha M. Benslimane,
  • Hebah A. Al-Khatib,
  • Zaina Al-Kanaani,
  • Einas Al-Kuwari,
  • Andrew Jeremijenko,
  • Anvar Hassan Kaleeckal,
  • Ali Nizar Latif,
  • Riyazuddin Mohammad Shaik,
  • Hanan F. Abdul-Rahim,
  • Gheyath K. Nasrallah,
  • Mohamed Ghaith Al-Kuwari,
  • Adeel A. Butt,
  • Hamad Eid Al-Romaihi,
  • Abdullatif Al-Khal,
  • Mohametabd H. Al-Thani,
  • Roberto Bertollini

DOI
https://doi.org/10.1038/s41467-022-28199-7
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

Read online

SARS-CoV-2 breakthrough infections in vaccinated individuals and reinfections in those with prior infection are a public health concern. Here, the authors show that viral loads of vaccine breakthrough infections and reinfections are generally lower than primary infections of unvaccinated individuals, potentially indicating lower infectiousness.