Nature Communications (Jan 2022)
Relative infectiousness of SARS-CoV-2 vaccine breakthrough infections, reinfections, and primary infections
- Laith J. Abu-Raddad,
- Hiam Chemaitelly,
- Houssein H. Ayoub,
- Patrick Tang,
- Peter Coyle,
- Mohammad R. Hasan,
- Hadi M. Yassine,
- Fatiha M. Benslimane,
- Hebah A. Al-Khatib,
- Zaina Al-Kanaani,
- Einas Al-Kuwari,
- Andrew Jeremijenko,
- Anvar Hassan Kaleeckal,
- Ali Nizar Latif,
- Riyazuddin Mohammad Shaik,
- Hanan F. Abdul-Rahim,
- Gheyath K. Nasrallah,
- Mohamed Ghaith Al-Kuwari,
- Adeel A. Butt,
- Hamad Eid Al-Romaihi,
- Abdullatif Al-Khal,
- Mohametabd H. Al-Thani,
- Roberto Bertollini
Affiliations
- Laith J. Abu-Raddad
- Infectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Cornell University
- Hiam Chemaitelly
- Infectious Disease Epidemiology Group, Weill Cornell Medicine-Qatar, Cornell University
- Houssein H. Ayoub
- Mathematics Program, Department of Mathematics, Statistics, and Physics, College of Arts and Sciences, Qatar University
- Patrick Tang
- Department of Pathology, Sidra Medicine
- Peter Coyle
- Hamad Medical Corporation
- Mohammad R. Hasan
- Department of Pathology, Sidra Medicine
- Hadi M. Yassine
- Biomedical Research Center, Member of QU Health, Qatar University
- Fatiha M. Benslimane
- Biomedical Research Center, Member of QU Health, Qatar University
- Hebah A. Al-Khatib
- Biomedical Research Center, Member of QU Health, Qatar University
- Zaina Al-Kanaani
- Hamad Medical Corporation
- Einas Al-Kuwari
- Hamad Medical Corporation
- Andrew Jeremijenko
- Hamad Medical Corporation
- Anvar Hassan Kaleeckal
- Hamad Medical Corporation
- Ali Nizar Latif
- Hamad Medical Corporation
- Riyazuddin Mohammad Shaik
- Hamad Medical Corporation
- Hanan F. Abdul-Rahim
- College of Health Sciences, QU Health, Qatar University
- Gheyath K. Nasrallah
- Biomedical Research Center, Member of QU Health, Qatar University
- Mohamed Ghaith Al-Kuwari
- Primary Health Care Corporation
- Adeel A. Butt
- Department of Population Health Sciences, Weill Cornell Medicine, Cornell University
- Hamad Eid Al-Romaihi
- Ministry of Public Health
- Abdullatif Al-Khal
- Hamad Medical Corporation
- Mohametabd H. Al-Thani
- Ministry of Public Health
- Roberto Bertollini
- Ministry of Public Health
- DOI
- https://doi.org/10.1038/s41467-022-28199-7
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 11
Abstract
SARS-CoV-2 breakthrough infections in vaccinated individuals and reinfections in those with prior infection are a public health concern. Here, the authors show that viral loads of vaccine breakthrough infections and reinfections are generally lower than primary infections of unvaccinated individuals, potentially indicating lower infectiousness.