Nature Communications (Oct 2020)
A fluoride-responsive genetic circuit enables in vivo biofluorination in engineered Pseudomonas putida
Abstract
Addition of fluorine to organic structures is a unique strategy for tuning molecular properties, but approaches to integrate fluorometabolites into the biochemistry of living cells are scarce. Here, the authors develop a fluoride-responsive genetic circuit to enable in vivo biofluorination in engineered Pseudomonas putida.