Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual

Nina V. Fuchs; Maximilian Schieck; Michaela Neuenkirch; Christiane Tondera; Heike Schmitz; Doris Steinemann; Gudrun Göhring; Renate König

Stem Cell Research (Jan 2020)

Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual

Nina V. Fuchs,
Maximilian Schieck,
Michaela Neuenkirch,
Christiane Tondera,
Heike Schmitz,
Doris Steinemann,
Gudrun Göhring,
Renate König

Affiliations

Nina V. Fuchs: Host‑Pathogen Interactions, Paul-Ehrlich-Institut, 63225 Langen, Germany
Maximilian Schieck: Department of Human Genetics, Hannover Medical School, Hannover, Germany
Michaela Neuenkirch: Host‑Pathogen Interactions, Paul-Ehrlich-Institut, 63225 Langen, Germany
Christiane Tondera: Host‑Pathogen Interactions, Paul-Ehrlich-Institut, 63225 Langen, Germany
Heike Schmitz: Host‑Pathogen Interactions, Paul-Ehrlich-Institut, 63225 Langen, Germany
Doris Steinemann: Department of Human Genetics, Hannover Medical School, Hannover, Germany
Gudrun Göhring: Department of Human Genetics, Hannover Medical School, Hannover, Germany
Renate König: Host‑Pathogen Interactions, Paul-Ehrlich-Institut, 63225 Langen, Germany; Immunity and Pathogenesis Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA; Corresponding author at: Host-Pathogen Interactions, Paul-Ehrlich-Str. 51-59, 63225 Langen, Germany.

Journal volume & issue: Vol. 42

Abstract

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Induced pluripotent stem cells (iPSCs) are a useful tool to investigate pathomechanistic and cellular processes due to their differentiation potential into different somatic cell types in vitro. Here, we have generated iPSCs from an apparently healthy male individual using an integration-free reprogramming method. The resulting iPSCs are pluripotent and display a normal karyotype. Furthermore, we demonstrate that this iPSC line can be differentiated into all three germ layers. Keywords: Induced pluripotent stem cells from an apparently healthy individual, Induced Pluripotent stem cells capable of differentiation into all three germ layers

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

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