Nature Communications (Sep 2019)
Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung
Abstract
Functional diversity of tissue-resident macrophages and signals governing their ontogeny and turnover remain unknown for the majority of tissues. Here the authors describe two phenotypically and functionally distinct long-lived populations of lung interstitial macrophages and their putative blood-derived monocytic precursor.