A case of false positive Troponin I in a patient affected by cryoglobulinemic vasculitis
M. Bellan,
M. Pirisi,
G. Bellomo,
P.P. Sainaghi
Affiliations
M. Bellan
Department of Translational Medicine, Università del Piemonte Orientale UPO, Novara; Division of Internal Medicine, Immunorheumatology Unit, AOU Maggiore della Carità, Novara
M. Pirisi
Department of Translational Medicine, Università del Piemonte Orientale UPO, Novara; Division of Internal Medicine, Immunorheumatology Unit, AOU Maggiore della Carità, Novara; IRCAD (Interdisciplinary Reseach Center of Autoimmune Diseases), Novara
G. Bellomo
Department of Health Sciences, Università del Piemonte Orientale UPO, Novara
P.P. Sainaghi
Division of Internal Medicine, Immunorheumatology Unit, AOU Maggiore della Carità, Novara; IRCAD (Interdisciplinary Reseach Center of Autoimmune Diseases), Novara
Troponin I (TnI) false positive results have been reported in patients affected by immune disorders. We report the case of a 74-year-old woman affected by cryoglobulinemic vasculitis, admitted to the Emergency Room because of a lipotimic episode. A marked elevation of TnI plasma concentration was confirmed in multiple determinations, despite the absence of symptoms or electrocardiogram findings suggesting myocardial infarction. TnI plasma concentration was reported normal after re-testing with a different commercial kit. A false TnI positivity should be considered in patients with immune disorders, especially if seropositive for rheumatoid factor, when the clinical context does not suggest myocardial infarction.
