International Journal of Nanomedicine (Sep 2022)
Microfluidic Methods in Janus Particle Synthesis
Abstract
Muhammad Saqib,1 Phong A Tran,2 Batur Ercan,3– 5 E Yegan Erdem1,6 1Department of Mechanical Engineering, Bilkent University, Ankara, Turkey; 2Queensland University of Technology (QUT), Brisbane, QLD, 4000, Australia; 3Department of Metallurgical and Materials Engineering, Middle East Technical University, Ankara, Turkey; 4Biomedical Engineering Program, Middle East Technical University, Ankara, Turkey; 5BIOMATEN, Center of Excellence in Biomaterials and Tissue Engineering, Middle East Technical University, Ankara, 06800, Turkey; 6National Nanotechnology Research Center (UNAM), Ankara, TurkeyCorrespondence: E Yegan Erdem, Bilkent University, Mechanical Engineering, EA 122, Bilkent, Ankara, 06800, Turkey, Tel +90 312 290 3068, Email [email protected]: Janus particles have been at the center of attention over the years due to their asymmetric nature that makes them superior in many ways to conventional monophase particles. Several techniques have been reported for the synthesis of Janus particles; however, microfluidic-based techniques are by far the most popular due to their versatility, rapid prototyping, low reagent consumption and superior control over reaction conditions. In this review, we will go through microfluidic-based Janus particle synthesis techniques and highlight how recent advances have led to complex functionalities being imparted to the Janus particles.Keywords: anisotropy, droplet-based, asymmetric, nanoparticles, multi-functionality
