Doppler imaging detects bacterial infection of living tissue

Honggu Choi; Zhe Li; Zhen Hua; Jessica Zuponcic; Eduardo Ximenes; John J. Turek; Michael R. Ladisch; David D. Nolte

doi:10.1038/s42003-020-01550-8

Communications Biology (Feb 2021)

Doppler imaging detects bacterial infection of living tissue

Honggu Choi,
Zhe Li,
Zhen Hua,
Jessica Zuponcic,
Eduardo Ximenes,
John J. Turek,
Michael R. Ladisch,
David D. Nolte

Affiliations

Honggu Choi: Department of Physics and Astronomy, Purdue University
Zhe Li: Department of Physics and Astronomy, Purdue University
Zhen Hua: Department of Physics and Astronomy, Purdue University
Jessica Zuponcic: Department of Agricultural and Biological Engineering and the Laboratory of Renewable Resources Engineering, Purdue University
Eduardo Ximenes: Department of Agricultural and Biological Engineering and the Laboratory of Renewable Resources Engineering, Purdue University
John J. Turek: Department of Basic Medical Science, Purdue University
Michael R. Ladisch: Department of Agricultural and Biological Engineering and the Laboratory of Renewable Resources Engineering, Purdue University
David D. Nolte: Department of Physics and Astronomy, Purdue University

DOI: https://doi.org/10.1038/s42003-020-01550-8
Journal volume & issue: Vol. 4, no. 1
pp. 1 – 10

Abstract

Read online

Honggu Choi et al. use biodynamic Doppler imaging to monitor bacterial infection of 3D living tissue and describe changes in the intracellular motions of living host tissue induced by early-stage infection. This work demonstrates the potential for the clinical use of this method to test for antibiotic-resistant infections.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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