EFFECT OF MORINGA (Moringa oleifera) LEAF FLOUR ETHANOL EXTRACT ON REDUCTION OF BLOOD GLUCOSE IN MALE WISTAR STRAIN RATS INDUCED BY ALLOXAN

Abstract

This study is to determine the effect of giving ethanol extract of moringa leaf flour (Moringa oleifera) on reducing blood glucose levels of alloxan-induced Wistar Rattus norvegicus male rats. Using a true experimental design with a randomized pre and post control group approach. The sample used consisted of 35 male Wistar white rats. Data collection using simple random sampling technique. Paired t test gives the results of p<0.05 in all treatment groups, meaning that there are differences in fasting blood glucose levels of hyperglycemic rats before and after treatment. One way ANOVA test gave the result of p<0.001, meaning that all treatment groups showed a significant difference in the mean difference in fasting blood glucose levels before and after treatment. LSD post hoc test results showed a significant mean difference in fasting blood glucose levels before and after treatment of P1 and P2 with all treatment groups (p<0.001). Probit analysis test obtained ED50=1447,84 mg/kgBB.

Keywords

• diabetes
• tepung daun kelor
• moringa oleifera