Cleaving HIV-1 provirus from ART-suppressed patient-derived resting CD4 T Cells using Cpf1/crRNA-array ribonucleotide protein packaged by CD4-targeting lentivirus-like particle

• W. Hu,
• Y. Cai,
• Y. Zhu,
• F. Li,
• A.O. Stella,
• P. Tebas,
• K. Mounzer,
• J. Kostman,
• S. Turville,
• L. Montaner

Affiliations

W. Hu

Department of Pathology and Laboratory Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, USA

Y. Cai

HIV-1 Immunopathogenesis Laboratory, Wistar Institute, Philadelphia, USA

Y. Zhu

Department of Pathology and Laboratory Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, USA

F. Li

Department of Pathology and Laboratory Medicine, Temple University Lewis Katz School of Medicine, Philadelphia, USA

A.O. Stella

Kirby Institute, University of New South Wales, Sydney, Australia

P. Tebas

Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA

K. Mounzer

Philadelphia Field Initiating Group for HIV-1 Trials, Philadelphia, USA

J. Kostman

Philadelphia Field Initiating Group for HIV-1 Trials, Philadelphia, USA

S. Turville

Kirby Institute, University of New South Wales, Sydney, Australia

L. Montaner

HIV-1 Immunopathogenesis Laboratory, Wistar Institute, Philadelphia, USA