Transcriptomics-Guided In Silico Drug Repurposing: Identifying New Candidates with Dual-Stage Antiplasmodial Activity

• Joyce V. B. Borba,
• Beatriz Rosa de Azevedo,
• Larissa A. Ferreira,
• Aline Rimoldi,
• Luís C. Salazar Alvarez,
• Juliana Calit,
• Daniel Y. Bargieri,
• Fabio T. M. Costa,
• Carolina Horta Andrade

Affiliations

Joyce V. B. Borba

Laboratory for Molecular Modeling and Drug Design (LabMol), Faculdade de Farmacia, Universidade Federal de Goias, Goiânia, Goiás, Brazil

Beatriz Rosa de Azevedo

Laboratory for Molecular Modeling and Drug Design (LabMol), Faculdade de Farmacia, Universidade Federal de Goias, Goiânia, Goiás, Brazil

Larissa A. Ferreira

Laboratory of Tropical DiseasesProf. Dr. Luiz Jacintho da Silva, Department of Genetics Evolution, Microbiology and Immunology, University of Campinas, Campinas, São Paulo, Brazil

Aline Rimoldi

Laboratory of Tropical DiseasesProf. Dr. Luiz Jacintho da Silva, Department of Genetics Evolution, Microbiology and Immunology, University of Campinas, Campinas, São Paulo, Brazil

Luís C. Salazar Alvarez

Laboratory of Tropical DiseasesProf. Dr. Luiz Jacintho da Silva, Department of Genetics Evolution, Microbiology and Immunology, University of Campinas, Campinas, São Paulo, Brazil

Juliana Calit

Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, São Paulo, Brazil

Daniel Y. Bargieri

Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, São Paulo, Brazil

Fabio T. M. Costa

Laboratory of Tropical DiseasesProf. Dr. Luiz Jacintho da Silva, Department of Genetics Evolution, Microbiology and Immunology, University of Campinas, Campinas, São Paulo, Brazil

Carolina Horta Andrade

Laboratory for Molecular Modeling and Drug Design (LabMol), Faculdade de Farmacia, Universidade Federal de Goias, Goiânia, Goiás, Brazil