Neuromotor prosthetic to treat stroke-related paresis: N-of-1 trial

Abstract

Serruya et al. test in an N-of-1 trial whether a wearable, powered exoskeletal orthosis, driven by a percutaneous, implanted brain–computer interface can restore voluntary upper extremity function following chronic hemiparesis subsequent to a cerebral subcortical stroke. Using this approach, voluntary opening of the paralyzed hand is restored.