Rates of intravenous thrombolysis and endovascular therapy for acute ischaemic stroke in China between 2019 and 2020

Qing Ye; Feifei Zhai; Baohua Chao; Lei Cao; Yun Xu; Peilan Zhang; Hongxing Han; Lihua Wang; Bing Xu; Wenhuo Chen; Changming Wen; Shouchun Wang; Runqing Wang; Liyong Zhang; Liqun Jiao; Sheng Liu; Yi-Cheng Zhu; Long-De Wang

The Lancet Regional Health. Western Pacific (Apr 2022)

Rates of intravenous thrombolysis and endovascular therapy for acute ischaemic stroke in China between 2019 and 2020

Qing Ye,
Feifei Zhai,
Baohua Chao,
Lei Cao,
Yun Xu,
Peilan Zhang,
Hongxing Han,
Lihua Wang,
Bing Xu,
Wenhuo Chen,
Changming Wen,
Shouchun Wang,
Runqing Wang,
Liyong Zhang,
Liqun Jiao,
Sheng Liu,
Yi-Cheng Zhu,
Long-De Wang

Affiliations

Qing Ye: Department of Neurology, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China; The General Office of Stroke Prevention Project Committee, National Health Commission of the People's Republic of China, Beijing, China
Feifei Zhai: Department of Neurology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Science, Beijing, China
Baohua Chao: The General Office of Stroke Prevention Project Committee, National Health Commission of the People's Republic of China, Beijing, China
Lei Cao: The General Office of Stroke Prevention Project Committee, National Health Commission of the People's Republic of China, Beijing, China
Yun Xu: Department of Neurology, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China
Peilan Zhang: Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China
Hongxing Han: Department of Neurology, Linyi People's Hospital, Shandong, China
Lihua Wang: Department of Neurology, The Second Affiliated Hospital, Harbin Medical University, Harbin, China
Bing Xu: Department of Neurology and Neuroscience, Shenyang First People's Hospital, Liaoning, China
Wenhuo Chen: Department of Neurointervention, Zhangzhou affiliated Hospital of Fujian Medical University, Fujian, China
Changming Wen: Department of Neurology, Nanyang Central Hospital, Nanyang, China
Shouchun Wang: Department of Neurology, The First Hospital of Jilin University, Jilin, China
Runqing Wang: Department of Neurology, Zhengzhou Central Hospital, Zhengzhou, China
Liyong Zhang: Department of Neurosurgery, Liaocheng People's Hospital, Shandong, China
Liqun Jiao: Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China
Sheng Liu: Department of Interventional Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
Yi-Cheng Zhu: Department of Neurology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Science, Beijing, China; Corresponding author at: Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Science, No. 1, Shuaifuyuan, Wangfujing, Beijing 100730, China.
Long-De Wang: The General Office of Stroke Prevention Project Committee, National Health Commission of the People's Republic of China, Beijing, China; School of Public Health, Peking University, Beijing, China; Corresponding author at: The General Office of Stroke Prevention Project Committee, National Health Commission of the People's Republic of China, No. 118, Guang'anmen Inner Street, Beijing 100053, China.

Journal volume & issue: Vol. 21
p. 100406

Abstract

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Summary: Background: In recent years, a series of initiatives have been launched to promote intravenous thrombolysis (IVT) and endovascular therapy (EVT) for acute ischaemic stroke (AIS) in China. We aimed to update the rates of IVT and EVT in China between 2019 and 2020 and to evaluate the current IVT and EVT according to hospital grades. Methods: Cross-sectional data on patients receiving IVT/EVT were derived from the Bigdata Observatory platform for Stroke of China (BOSC). The monthly number of discharged patients with a principal diagnosis of AIS was derived from the first pages of medical records of each hospital. The rates and information of IVT and EVT were analysed according to hospital grades. Findings: During this period, 938 tertiary hospitals and 786 secondary hospitals from 31 provinces continuously reported data to the BOSC. The overall IVT rate for AIS was 5·64%, and the EVT rate was 1·45%. The IVT rate in secondary hospitals was higher than that in tertiary hospitals (6·39% vs. 5·39%, P < 0·001), whereas the EVT rate in secondary hospitals was much lower than that in tertiary hospitals (0·29% vs. 1·84%, P < 0·001). Significant differences in demographic and clinical characteristics of patients receiving IVT/EVT were also shown between tertiary and secondary hospitals. Interpretation: The rates of IVT and EVT for AIS have greatly increased in China, but there is still a large gap compared with developed countries. Hospital inhomogeneity in IVT and EVT suggests the importance of developing a region-specific network for stroke treatment. Funding: None.

Published in The Lancet Regional Health. Western Pacific

ISSN: 2666-6065 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Medicine: Public aspects of medicine
Website: https://www.thelancet.com/journals/lanwpc/home

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