Nature Communications (Feb 2021)

Spatially mapped single-cell chromatin accessibility

  • Casey A. Thornton,
  • Ryan M. Mulqueen,
  • Kristof A. Torkenczy,
  • Andrew Nishida,
  • Eve G. Lowenstein,
  • Andrew J. Fields,
  • Frank J. Steemers,
  • Wenri Zhang,
  • Heather L. McConnell,
  • Randy L. Woltjer,
  • Anusha Mishra,
  • Kevin M. Wright,
  • Andrew C. Adey

DOI
https://doi.org/10.1038/s41467-021-21515-7
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 16

Abstract

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Spatial orientation of cells in an interconnected network is lost in high-throughput single-cell epigenomic assays. Here the authors present sciMAP-ATAC to produce spatially resolved single-cell ATAC-seq data.