Nature Communications (May 2022)
Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injury
- Laura Empl,
- Alexandra Chovsepian,
- Maryam Chahin,
- Wing Yin Vanessa Kan,
- Julie Fourneau,
- Valérie Van Steenbergen,
- Sanofer Weidinger,
- Maite Marcantoni,
- Alexander Ghanem,
- Peter Bradley,
- Karl Klaus Conzelmann,
- Ruiyao Cai,
- Alireza Ghasemigharagoz,
- Ali Ertürk,
- Ingrid Wagner,
- Mario Kreutzfeldt,
- Doron Merkler,
- Sabine Liebscher,
- Florence M. Bareyre
Affiliations
- Laura Empl
- Institute of Clinical Neuroimmunology, University Hospital, LMU Munich
- Alexandra Chovsepian
- Institute of Clinical Neuroimmunology, University Hospital, LMU Munich
- Maryam Chahin
- Institute of Clinical Neuroimmunology, University Hospital, LMU Munich
- Wing Yin Vanessa Kan
- Institute of Clinical Neuroimmunology, University Hospital, LMU Munich
- Julie Fourneau
- Institute of Clinical Neuroimmunology, University Hospital, LMU Munich
- Valérie Van Steenbergen
- Institute of Clinical Neuroimmunology, University Hospital, LMU Munich
- Sanofer Weidinger
- Institute of Clinical Neuroimmunology, University Hospital, LMU Munich
- Maite Marcantoni
- Institute of Clinical Neuroimmunology, University Hospital, LMU Munich
- Alexander Ghanem
- Max von Pettenkofer-Institute, Virology, Faculty of Medicine, & Gene Center, LMU Munich
- Peter Bradley
- Institute of Clinical Neuroimmunology, University Hospital, LMU Munich
- Karl Klaus Conzelmann
- Max von Pettenkofer-Institute, Virology, Faculty of Medicine, & Gene Center, LMU Munich
- Ruiyao Cai
- Institute for Tissue Engineering and Regenerative Medicine (iTERM), Helmholtz Zentrum München
- Alireza Ghasemigharagoz
- Institute for Tissue Engineering and Regenerative Medicine (iTERM), Helmholtz Zentrum München
- Ali Ertürk
- Institute for Tissue Engineering and Regenerative Medicine (iTERM), Helmholtz Zentrum München
- Ingrid Wagner
- Department of Pathology and Immunology, Division of Clinical Pathology, CMU, University & University Hospitals of Geneva, Rue Michel-Servet
- Mario Kreutzfeldt
- Department of Pathology and Immunology, Division of Clinical Pathology, CMU, University & University Hospitals of Geneva, Rue Michel-Servet
- Doron Merkler
- Department of Pathology and Immunology, Division of Clinical Pathology, CMU, University & University Hospitals of Geneva, Rue Michel-Servet
- Sabine Liebscher
- Institute of Clinical Neuroimmunology, University Hospital, LMU Munich
- Florence M. Bareyre
- Institute of Clinical Neuroimmunology, University Hospital, LMU Munich
- DOI
- https://doi.org/10.1038/s41467-022-29992-0
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 16
Abstract
Which contralesional circuits adapt after traumatic brain injury (TBI) is unclear. Here the authors used in vivo imaging, retrograde labeling, rabies tracing, clearing and functional imaging to demonstrate that callosal neurons selectively adapt after TBI in mice.
