Yellow DS5R polymeric film modified glassy carbon electrode for voltametric assay of uric acid: sensor for uric acid

Abstract

This work focuses on the development of a novel and affordable yellow DS5R polymeric film on the glassy carbon electrode surface (Po-YDS5R/GCE) for the detection of uric acid (UAC). Po-YDS5R/GCE was effectively developed using cyclic potentiodynamic polyme­rization technique. The sweep rate study revealed that the overall electrode reaction is diffusion-controlled. The linear range of 10-60 µM of UAC was used to compute the limit of quantification and limit of detection, and the results yield 3.12 and 0.87 µM, res­pec­ti­vely. The interference of dopamine on the electrooxidation of UAC was tested at the developed sensor. It was discovered that the modified sensor allows selective detection of UAC. These impressive outcomes showed that a simple and less-costly Po-YDS5R/GCE sensor has a significant potential to make significant improvement over current electro­chemical sensor technology.

Keywords

• Reactive dye
• electro-polymerization
• electroactive biomolecules
• cyclic voltammetry