VESSEL WALL STIFFNESS IN ARTERIAL HYPERTENSION AND OPPORTUNITIES FOR ITS MODULATION

Abstract

Arterial hypertension (AH) is a serious medical and social problem due to its complications leading to disability. Recently, there is a lot of attention paid to markers evaluation for cardiovascular pathology — endothelial dysfunction, arteries elasticity decline, increased pulse wave velocity (vascular wall stiffness) and studying of an influence of various antihypertension treatments. Current article focuses on the modern influences on remodeling of vessel wall in AH and opportunities of its pharmacological correction with angiotensine converting enzyme inhibitors, calcium channel blockers and beta-blockers as monotherapy and combination.

Keywords

• артериальная гипертония
• жесткость сосудистой стенки
• ингибиторы ангиотензин-превращающего фермента
• антагонисты кальция
• β-адреноблокаторы
• комбинированная антигипертензивная терапия