A spike-timing-dependent plasticity rule for dendritic spines

Sabrina Tazerart; Diana E. Mitchell; Soledad Miranda-Rottmann; Roberto Araya

doi:10.1038/s41467-020-17861-7

Nature Communications (Aug 2020)

A spike-timing-dependent plasticity rule for dendritic spines

Sabrina Tazerart,
Diana E. Mitchell,
Soledad Miranda-Rottmann,
Roberto Araya

Affiliations

Sabrina Tazerart: Department of Neurosciences, Faculty of Medicine, University of Montreal
Diana E. Mitchell: Department of Neurosciences, Faculty of Medicine, University of Montreal
Soledad Miranda-Rottmann: Department of Neurosciences, Faculty of Medicine, University of Montreal
Roberto Araya: Department of Neurosciences, Faculty of Medicine, University of Montreal

DOI: https://doi.org/10.1038/s41467-020-17861-7
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 16

Abstract

Read online

The structural organization of excitatory inputs supporting spike-timing-dependent plasticity (STDP) in dendritic spines remains unknown. Using a spine STDP protocol, the authors uncover the STDP rules for single, clustered and distributed dendritic spines in the basal dendrites of layer 5 pyramidal neurons in juvenile mice.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal