442 CAIX targeted CAR-T cells exhibited antitumor efficacy on renal cell carcinoma (RCC) patient derived organotypic tumor spheroids (PDOTS)

• Sabina Signoretti,
• Toni K Choueiri,
• Cloud Paweletz,
• Kun Huang,
• Yufei Wang,
• Gordon Freeman,
• Alicia Buck,
• Gabriella Kastrunes,
• Marion Grimaud,
• Atef Fayed,
• Luann Zerefa,
• Brandon Piel,
• Elena Ivanova,
• Miriam Ficial,
• Jon Wee,
• David Barbie,
• Wayne Marasco,
• Andras-Gabor Miklosi,
• Tran Thai,
• Ming-Ru Wu

Affiliations

Sabina Signoretti

3Brigham and Women’s Hospital, Boston, MA, USA

Toni K Choueiri

1Dana-Farber Cancer Institute, Boston, MA, USA

Cloud Paweletz

1Dana-Farber Cancer Institute, Boston, MA, USA

Kun Huang

1Dana-Farber Cancer Institute, Boston, MA, USA

Yufei Wang

1Dana-Farber Cancer Institute, Boston, MA, USA

Gordon Freeman

1Dana-Farber Cancer Institute, Boston, MA, USA

Alicia Buck

1Dana-Farber Cancer Institute, Boston, MA, USA

Gabriella Kastrunes

1Dana-Farber Cancer Institute, Boston, MA, USA

Marion Grimaud

1Dana-Farber Cancer Institute, Boston, MA, USA

Atef Fayed

1Dana-Farber Cancer Institute, Boston, MA, USA

Luann Zerefa

1Dana-Farber Cancer Institute, Boston, MA, USA

Brandon Piel

1Dana-Farber Cancer Institute, Boston, MA, USA

Elena Ivanova

1Dana-Farber Cancer Institute, Boston, MA, USA

Miriam Ficial

3Brigham and Women’s Hospital, Boston, MA, USA

Jon Wee

3Brigham and Women’s Hospital, Boston, MA, USA

David Barbie

1Dana-Farber Cancer Institute, Boston, MA, USA

Wayne Marasco

1Dana-Farber Cancer Institute, Boston, MA, USA

Andras-Gabor Miklosi

2ONI, Oxford, UK

Tran Thai

1Dana-Farber Cancer Institute, Boston, MA, USA

Ming-Ru Wu

4Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA