Atorvastatin in the secondary prevention of cardiovascular diseases

Abstract

Clinical manifestations of the atherosclerotic process are leading causes of mortality, morbidity and disability in the adult population of the developed countries all over the world. Many years of research have established a clear relationship between the risk of cardiovascular disease and high cholesterol level. Numerous global epidemiological studies, such as, for example, the Framingham Heart Study [1] and INTERHEART [2], provided solid evidence confirming that statement. Moreover, randomized clinical trials of lipid-lowering interventions over the past 10-15 years demonstrate that greater cholesterol reduction is associated with a significant decrease in the risk of complications.

Keywords

• сердечно-сосудистые заболевания
• профилактика
• статины
• аторвастатин
• cardiovascular disease
• prevention
• statins
• atorvastatin