Toxicological and hygienic regulation and assessment of danger of the new fungicide-cyflufenamid

Abstract

Toxicodynamic peculiarities of the new fun­gicide – cyflufenamid were studied. It was found that in accordance with hygienic classification of pesticides, cyflufe­namid is referred to the 3rd class of hazard (moderately hazardous). It was shown that liver is the primary target organ of cyflufenamid action, thyroid gland, heart, kidneys, brain are secondary. It was established that cyflufenamid is mic­rosomal enzyme inducer. Acceptable daily dose of cyflufenamid for humans was substantiated on level of 0,01 mg/kg.

Keywords

• cyflufenamid
• fungicides
• acceptable daily dose
• toxicity
• hazardous class