Folia Histochemica et Cytobiologica (Jun 2006)

NK cell depletion and recovery in SCID mice treated with anti-NK1.1 antibody.

  • Jerzy Kawiak,
  • Danuta Wasilewska,
  • Grazyna Hoser,
  • Joanna Kulesza

DOI
https://doi.org/10.5603/4573
Journal volume & issue
Vol. 44, no. 2
pp. 93 – 96

Abstract

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The anti-NK1.1 antibody produced by PK136 hybridoma cell line administered subcutaneously to SCID mice effectively decreased the level of peripheral blood NK cells and weight of the spleen for 3-4 days. The antibody treatment did not harm the general state of the animal, and may be practically applied in xenograft experiments.