Scientific Reports (Jan 2024)

Efficacy of an eHealth self-management program in reducing irritable bowel syndrome symptom severity: a randomized controlled trial

  • Jun Tayama,
  • Toyohiro Hamaguchi,
  • Kohei Koizumi,
  • Ryodai Yamamura,
  • Ryo Okubo,
  • Jun-ichiro Kawahara,
  • Kenji Inoue,
  • Atsushi Takeoka,
  • Shin Fukudo

DOI
https://doi.org/10.1038/s41598-023-50293-z
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 11

Abstract

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Abstract This study aimed to verify whether an eHealth-based self-management program can reduce irritable bowel syndrome (IBS) symptom severity. An open-label simple randomized controlled trial was conducted that compared an intervention group (n = 21) participating in an eHealth self-management program, which involved studying IBS-related information from an established self-help guide followed by in-built quizzes, with a treatment-as-usual group (n = 19) that, except for pharmacotherapy, had no treatment restrictions. Participants were female Japanese university students. The eHealth group received unlimited access to the self-management program for 8 weeks on computers and mobile devices. The primary outcome, participants’ severity of IBS symptoms assessed using the IBS-severity index (IBS-SI), and the secondary outcomes of participants’ quality of life, gut bacteria, and electroencephalography alpha and beta power percentages were measured at baseline and 8 weeks. A significant difference was found in the net change in IBS-SI scores between the eHealth and treatment-as-usual groups, and the former had significantly lower IBS-SI scores following the 8-week intervention than at baseline. Moreover, there was a significant difference in the net change in phylum Cyanobacteria between the eHealth and treatment-as-usual groups. Thus, the eHealth-based self-management program successfully reduced the severity of IBS symptoms.