Documentation of bioactive principles of the flower from Caralluma retrospiciens (Ehrenb) and in vitro antibacterial activity – Part B

Abstract

The purpose of this study was to explore the biocomponents of flowers from Caralluma retrospiciens (Ehrenb). The study investigated the FT-IR and GC–MS spectral analysis of flower from C. retrospiciens (Ehrenb). A flower concentrate (FC) was prepared and the functional groups were determined by FT-IR spectroscopy study. FT-IR analysis showed the presence of significant compounds at frequency 3287.45, 2850.32, 2595.91, 2524.69, 2041.07 cm−1. The GC–MS study demonstrated the presence of unique pharmaceutically important compounds. The extract was characterized by the presence of unique compounds such as “7,8-Epoxylanostan-11-ol, 3-acetoxy”, “Pregnan-20-one, 5,6-epoxy-3-hydroxy-, (3á,5á,6á)-”, “Benzenepropanoic acid, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-, methyl ester”, “Hexadecanoic acid, methyl ester”, “Dasycarpidan-1-methanol, acetate”, etc. The antibacterial effect of the FC showed a wide spectrum of activity against the screened human pathogenic bacteria. The activity was predominantly against Gram-negative bacteria.

Keywords

• Desert plant
• Caralluma retrospiciens (Ehrenb)
• Flowers
• Phytochemicals
• Spectral analysis
• Antibacterial studies