PLoS ONE (Jan 2021)

Right bundle branch block is not associated with worse short- and mid-term outcome after transcatheter aortic valve implantation.

  • Maren Weferling,
  • Christoph Liebetrau,
  • Matthias Renker,
  • Ulrich Fischer-Rasokat,
  • Yeoung-Hoon Choi,
  • Christian W Hamm,
  • Won-Keun Kim

DOI
https://doi.org/10.1371/journal.pone.0253332
Journal volume & issue
Vol. 16, no. 6
p. e0253332

Abstract

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BackgroundTranscatheter aortic valve implantation (TAVI) is the standard treatment option for patients with severe aortic stenosis (AS) at intermediate or high surgical risk. Preexisting right bundle branch block (RBBB) is a strong predictor of new pacemaker implantation (PPM) after TAVI, and previous data indicate a worse short- and long-term outcome of patients. The aim of this study was to investigate whether preexisting RBBB has an effect on the short- and mid-term outcome of patients undergoing TAVI in a German high-volume TAVI center.MethodsFor the present retrospective analysis, a total of 1,891 patients with native severe AS with successful TAVI without preexisting PPM were included. The primary endpoint was all-cause mortality after 30 days and 12 months. Baseline RBBB was present in 190 (10.1%) of cases.ResultsPatients with preexisting RBBB had a considerably higher rate of new PPM after TAVI compared with patients without RBBB (87/190 [45.8%] vs. 219/1,701 [12.9%]; pConclusionPreexisting RBBB is a common finding in patients with severe AS undergoing TAVI and is associated with considerably higher PPM rates but not with worse short- and mid-term outcome.