Clinical Case Reports (Apr 2021)

Response to pegylated interferon in a COVID‐19–positive elderly woman with primary myelofibrosis treated with ruxolitinib

  • Arthur E. Frankel,
  • Renuka Reddy,
  • Kayla R. DeSuza,
  • Khaled Deeb,
  • Aaron F. Carlin,
  • Davey Smith,
  • Yushuang Xie,
  • Eknath Naik,
  • Richard T. Silver,
  • Hans C. Hasselbalch

DOI
https://doi.org/10.1002/ccr3.3997
Journal volume & issue
Vol. 9, no. 4
pp. 2228 – 2235

Abstract

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Abstract An 83‐year‐old female had asymptomatic SARS‐CoV‐2 infection while taking ruxolitinib. She remained RT‐PCR positive for viral RNA for >120 days, and Pegylated interferon for 4 weeks led to viral RNA clearance. The observations support combination therapy of ruxolitinib + interferon for COVID‐19.

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