Communications Biology (Jun 2021)

A porcine brain-wide RNA editing landscape

  • Jinrong Huang,
  • Lin Lin,
  • Zhanying Dong,
  • Ling Yang,
  • Tianyu Zheng,
  • Weiwang Gu,
  • Yan Zhang,
  • Tailang Yin,
  • Evelina Sjöstedt,
  • Jan Mulder,
  • Mathias Uhlén,
  • Karsten Kristiansen,
  • Lars Bolund,
  • Yonglun Luo

DOI
https://doi.org/10.1038/s42003-021-02238-3
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 12

Abstract

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Huang et al performed a genome-wide RNA editing investigation in the porcine brain in which they found over 680,000 A-to-I RNA editing sites. They identified conserved recoding events between pig and human brains thus providing an extensive resource to aid our understanding of the evolutionary importance of post-transcriptional RNA editing.