Nature Communications (May 2016)

The extracellular interactome of the human adenovirus family reveals diverse strategies for immunomodulation

  • Nadia Martinez-Martin,
  • Sree R. Ramani,
  • Jason A. Hackney,
  • Irene Tom,
  • Bernd J. Wranik,
  • Michelle Chan,
  • Johnny Wu,
  • Maciej T. Paluch,
  • Kentaro Takeda,
  • Philip E. Hass,
  • Hilary Clark,
  • Lino C. Gonzalez

DOI
https://doi.org/10.1038/ncomms11473
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 16

Abstract

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Viruses interact with their hosts via secreted and membrane-bound proteins to affect host immune responses and virulence. Here the authors contribute to our understanding of this relationship with an extracellular interaction map of human and adenoviral E3 immunomodulatory proteins.