Generation of IBMS-iPSC-015, -016, -017 human induced pluripotent stem cells (IBMSi013-A, IBMSi014-A, and IBMSi015-A) derived from patients with atrial fibrillation

Yueh-Ting Chiu; Ming-Heng Tsai; Darien Zhing-Herr Chan; Hui-Wen Ko; Huai-En Lu; Chi-Ying F. Huang; Yenn-Jiang Lin; Shih-Lin Chang; Li-Wei Lo; Ching-Ying Huang; Yu-Feng Hu; Patrick C.H. Hsieh; Shih-Ann Chen

Stem Cell Research (Jul 2021)

Generation of IBMS-iPSC-015, -016, -017 human induced pluripotent stem cells (IBMSi013-A, IBMSi014-A, and IBMSi015-A) derived from patients with atrial fibrillation

Yueh-Ting Chiu,
Ming-Heng Tsai,
Darien Zhing-Herr Chan,
Hui-Wen Ko,
Huai-En Lu,
Chi-Ying F. Huang,
Yenn-Jiang Lin,
Shih-Lin Chang,
Li-Wei Lo,
Ching-Ying Huang,
Yu-Feng Hu,
Patrick C.H. Hsieh,
Shih-Ann Chen

Affiliations

Yueh-Ting Chiu: Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
Ming-Heng Tsai: Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
Darien Zhing-Herr Chan: Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
Hui-Wen Ko: Food Industry Research and Development Institute, Hsinchu, Taiwan
Huai-En Lu: Food Industry Research and Development Institute, Hsinchu, Taiwan
Chi-Ying F. Huang: Institute of Biopharmaceutical Sciences, National Yang Ming University, Taipei, Taiwan
Yenn-Jiang Lin: Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Shih-Lin Chang: Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Li-Wei Lo: Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Ching-Ying Huang: Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
Yu-Feng Hu: Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan; Corresponding authors.
Patrick C.H. Hsieh: Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Corresponding authors.
Shih-Ann Chen: Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan; Heart Rhythm Center, Division of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan

Journal volume & issue: Vol. 54
p. 102419

Abstract

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Atrial fibrillation is the most common heart disease in the world, with around 35 million patients in 2020. Here we reported the generation of IBMS-iPSC-015-06, IBMS-iPSC-016-06, and IBMS-iPSC-017-02 as human induced pluripotent stem cell (iPSC) lines from patients’ peripheral blood mononuclear cells (PBMCs) with atrial fibrillation. The cell lines expressed properties of pluripotent stem cells, including pluripotent markers and the ability to differentiate into three germ layers. These cell lines served as suitable models for studying alternative therapies of atrial fibrillation.

Published in Stem Cell Research

ISSN: 1873-5061 (Print); 1876-7753 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Biology (General)
Website: https://www.journals.elsevier.com/stem-cell-research

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