Revista da Sociedade Brasileira de Medicina Tropical ()

Cacipacore virus as an emergent mosquito-borne Flavivirus

  • Mario Luis Garcia de Figueiredo,
  • Alberto Anastacio Amarilla,
  • Glauciane Garcia de Figueiredo,
  • Helda Liz Alfonso,
  • Veronica Lippi,
  • Felipe Gonçalves Motta Maia,
  • Felipe Alves Morais,
  • Cristóvão Alves da Costa,
  • Dyana Alves Henriques,
  • Edison Luis Durigon,
  • Luiz Tadeu Moraes Figueiredo,
  • Victor Hugo Aquino

DOI
https://doi.org/10.1590/0037-8682-0485-2016
Journal volume & issue
Vol. 50, no. 4
pp. 539 – 542

Abstract

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Abstract INTRODUCTION: Cacipacore virus (CPCV), a possible bird-associated flavivirus, has yet to be detected in mosquitoes. Our purpose is examining CPCV in mosquitoes from the Amazon region of Brazil. METHODS: Approximately 3,253 Culicidae (grouped into 264 pools) were collected from the Amazon region during 2002-2006 and analyzed using a Flavivirus genus-specific reverse transcription- polymerase chain reaction followed by nested polymerase chain reaction assay and by nucleotide sequencing of amplicons. RESULTS: Nucleotide sequences from five mosquito samples showed high similarity to the those of CPCV originally isolated in the Amazon region. CONCLUSIONS: This is the first report of CPCV-infected mosquitoes which has implications on the arbovirus maintenance in nature and transmission to man.

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