Communications Medicine (Sep 2022)

Increased very low frequency pulsations and decreased cardiorespiratory pulsations suggest altered brain clearance in narcolepsy

  • Matti Järvelä,
  • Janne Kananen,
  • Vesa Korhonen,
  • Niko Huotari,
  • Hanna Ansakorpi,
  • Vesa Kiviniemi

DOI
https://doi.org/10.1038/s43856-022-00187-4
Journal volume & issue
Vol. 2, no. 1
pp. 1 – 13

Abstract

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Järvelä et al. investigate if narcolepsy is associated with altered brain pulsations using ultrafast fMRI. They find differences in the brain pulsations between narcolepsy type 1 patients and healthy controls that may link to altered brain clearance in narcolepsy, have diagnostic potential and correlate with the severity of narcolepsy.