Vestnik Transplantologii i Iskusstvennyh Organov (May 2012)

PERIOPERATIVE PERIOD FOLLOWING HEART TRANSPLANTATION WITH SEVERE LEFT VENTRICULAR HYPERTROPHY

  • V. N. Poptsov,
  • E. A. Spirina,
  • V. V. Pchelnikov,
  • D. S. Ilyin,
  • V. A. Ilyinskiy,
  • I. D. Potapenko,
  • S. G. Uchrenkov,
  • N. A. Kuguneva

DOI
https://doi.org/10.15825/1995-1191-2012-2-6-14
Journal volume & issue
Vol. 14, no. 2
pp. 6 – 14

Abstract

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Use donor hearts with left ventricular hypertrophy (LVH) is controversial. This category of heart recipients has increasing risk of early graft failure. We proposed that heart transplantation (HT) with LVH ≥1.5 cm may be successful if performed in selective category patients from alternate transplant list. This study included 10 pati- ents (2 female and 8 male) at the age 26–62 (44 ± 3), who needed urgent HT. This study showed that recipients with LVH ≥1.5 cm demanded more high and long inotropic support with adrenalin and dopamine, more fre- quent use of levosimendan infusion (in 40% of cases) and intraaortic balloon conterpulsation (in 50% of cases). However we didn’t observed any difference in survival rate (90.0% vs 89.0%) and ICU time (4.8 ± 0.6 days vs 4.1 ± 0.4 days) between HT recipients with and without LVH. Our study showed that HT from donor with LVH ≥1.5 cm may be performed in patients, demanding urgent HT, with acceptable early posttransplant results.

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