Dermatology Reports (May 2025)

Cutaneous complications of cyclosporine: a case of drug-induced folliculitis in atopic dermatitis

  • Mohammad Al-Haddab,
  • Rema Alkahtani,
  • Faisal BinKhonain,
  • Amany Fathaddin

DOI
https://doi.org/10.4081/dr.2025.10242

Abstract

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Cyclosporine-induced folliculitis remains underreported and underrecognized in clinical practice, posing diagnostic challenges for dermatologists and clinicians. In this case report, we present a compelling case of cyclosporine-induced folliculitis. A 40-year-old patient with severe atopic dermatitis was treated with topical steroids, calcineurin inhibitor, and phototherapy for 6 months. After starting cyclosporine 150 mg, acne-like eruptions appeared, and a 4 mm skin biopsy revealed folliculitis and perifolliculitis. Cyclosporine-induced folliculitis is a rare adverse effect of cyclosporine therapy, requiring prompt management through dose adjustment, discontinuation, and adjunctive therapies.

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