Folia Medica (Apr 2021)

Unexpected hearing improvement after treatment with valganciclovir in a child with congenital cytomegalovirus infection

  • Silvia Palma,
  • Laura Mazzoni,
  • Maria Federica Roversi,
  • Cecilia Botti,
  • Daniele Monzani,
  • Alberto Berardi,
  • Elisabetta Genovese

DOI
https://doi.org/10.3897/folmed.63.e54665
Journal volume & issue
Vol. 63, no. 2
pp. 297 – 301

Abstract

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A 32-week preterm-born male with symptomatic congenital cytomegalovirus infection was treated with valganciclovir. He was also affected by congenital severe bilateral hearing loss and, unexpectedly, a normalization of the hearing threshold was reached at one year of age. The improvement of hearing level in relationship with both the late development of the auditory system and the administration of antiviral therapy is discussed. This case also highlights the importance of early diagnosis of congenital cytomegalovirus associated with close follow-up.

Keywords