The Road to Unconventional Detections: Paper-Based Microfluidic Chips
Yuhang Jin,
Aziz ur Rehman Aziz,
Bin Wu,
Ying Lv,
Hangyu Zhang,
Na Li,
Bo Liu,
Zhengyao Zhang
Affiliations
Yuhang Jin
Liaoning Key Laboratory of Integrated Circuit and Biomedical Electronic System, School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian 116024, China
Aziz ur Rehman Aziz
Liaoning Key Laboratory of Integrated Circuit and Biomedical Electronic System, School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian 116024, China
Bin Wu
China Certification and Inspection Group Liaoning Co., Ltd., Dalian 116039, China
Ying Lv
China Certification and Inspection Group Liaoning Co., Ltd., Dalian 116039, China
Hangyu Zhang
Liaoning Key Laboratory of Integrated Circuit and Biomedical Electronic System, School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian 116024, China
Na Li
Liaoning Key Laboratory of Integrated Circuit and Biomedical Electronic System, School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian 116024, China
Bo Liu
Liaoning Key Laboratory of Integrated Circuit and Biomedical Electronic System, School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian 116024, China
Zhengyao Zhang
School of Life Science and Pharmacy, Dalian University of Technology, Dalian 116024, China
Conventional detectors are mostly made up of complicated structures that are hard to use. A paper-based microfluidic chip, however, combines the advantages of being small, efficient, easy to process, and environmentally friendly. The paper-based microfluidic chips for biomedical applications focus on efficiency, accuracy, integration, and innovation. Therefore, continuous progress is observed in the transition from single-channel detection to multi-channel detection and in the shift from qualitative detection to quantitative detection. These developments improved the efficiency and accuracy of single-cell substance detection. Paper-based microfluidic chips can provide insight into a variety of fields, including biomedicine and other related fields. This review looks at how paper-based microfluidic chips are prepared, analyzed, and used to help with both biomedical development and functional integration, ideally at the same time.
