Rare Chromosomal Variants in Males with Hypogonadism: A Case Series From Tertiary Hospital in India

Abstract

Male hypogonadism refers to decrease in testosterone levels due to diminished activity of testes. Hypogonadism will result in infertility, absent or poor secondary sexual characteristics and abnormal genitalia. One of the important causes of male hypogonadism is sex chromosomal abnormalities. In present study we discuss 5 cases of hypogonadism which has resulted due to rare sex chromosomal abnormalities. Identification of these abnormalities is very important in management of these patients.

Keywords

• hypogonadism
• sex chromosomal abnormalities
• infertility
• klinefelter syndrome