Atomic structure of the Epstein-Barr virus portal

Cristina Machón; Montserrat Fàbrega-Ferrer; Daming Zhou; Ana Cuervo; José L. Carrascosa; David I. Stuart; Miquel Coll

doi:10.1038/s41467-019-11706-8

Nature Communications (Aug 2019)

Atomic structure of the Epstein-Barr virus portal

Cristina Machón,
Montserrat Fàbrega-Ferrer,
Daming Zhou,
Ana Cuervo,
José L. Carrascosa,
David I. Stuart,
Miquel Coll

Affiliations

Cristina Machón: Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST)
Montserrat Fàbrega-Ferrer: Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST)
Daming Zhou: Division of Structural Biology, University of Oxford
Ana Cuervo: Department of Macromolecular Structures, Centro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas (CNB-CSIC)
José L. Carrascosa: Department of Macromolecular Structures, Centro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas (CNB-CSIC)
David I. Stuart: Division of Structural Biology, University of Oxford
Miquel Coll: Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST)

DOI: https://doi.org/10.1038/s41467-019-11706-8
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 7

Abstract

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The Epstein-Barr virus (EBV) is a dangerous human pathogen responsible for mononucleosis and several types of cancers. Here the authors describe a high-resolution atomic structure of the EBV portal, which serves as the entrance and exit pore for the viral genome and is a potential pharmacological target for the development of antivirals.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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