Pharmacia (Jan 2021)

In vitro effects of synthetic muscimol and an extract from Amanita muscaria on human recombinant MAOB enzyme

  • Maria Voynova,
  • Aleksandar Shkondrov,
  • Ilina Krasteva,
  • Magdalena Kondeva-Burdina

DOI
https://doi.org/10.3897/pharmacia.68.e60705
Journal volume & issue
Vol. 68, no. 1
pp. 147 – 150

Abstract

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The effects of synthetic muscimol and an extract from Amanita muscaria, containing this compound on the activity of human recombinant MAOB enzyme (hMAOB) were studied. Muscimol had statistically significant inducing effect on hMAOB at concentrations 0.25–5 μM, while A. muscaria extract did not influence the enzyme activity at all.