Noninvasive assessment and risk factors of liver fibrosis in pediatric patients with beta thalassemia major using transient elastography

Abstract

Key messages For individuals with beta-thalassemia major, transient elastography is a noninvasive method for assessing liver fibrosis A further contributing factor to liver fibrosis in these patients is HCV infection acquired during transfusional therapy. Patients' advanced age and a history of numerous transfusions may increase their chance of developing liver fibrosis.

Keywords

• Transient elastography
• Beta-thalassemia major
• Iron overload
• HCV infection